Saxsons Group

Clinical evidence library · the manufacturer

Delta4 Phantom+ — what the literature says.

Six peer-reviewed studies anchor this page: error-detection sensitivity (Udee 2024), TG-218 action limits across 275 SRS/SBRT plans (Xia 2020), MR-linac adaptive-RT validation at 0.35 T (Cusumano 2020) and 1.5 T (Houweling 2017), pre-treatment IMRT cohort gamma analysis, and the original Delta4 device characterisation. Filter by use-case to see only the cards that matter to your programme.

6 peer-reviewed studies on this page
275 SRS / SBRT plans, 6 198 γ analyses (Xia 2020)
1 069 p-type diodes on two orthogonal panels
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Sensitivity to introduced plan errors (H&N + lung VMAT)
2 mm
MLC position
Collimator rotation
1.5%
MU change
GPR drops below the 95 % action limit at each of these error magnitudes — a clear stop-go signal for the physicist.
Error detection 2024
95% gamma-passing-rate action threshold — Delta4 crosses it at MLC ≥ 2 mm and collimator rotation ≥ 2°

Delta4-based dosimetric error detection in volumetric-modulated arc therapy: clinical significance and implications

Journal of Medical Physics 49(1):56–63 — Udee et al.

Gamma passing rate at increasing MU error (lower = larger detected error)
MU + 1.5 % (small)
91.7%
MU + 3.0 % (medium)
75%
MU + 4.5 % (large)
49.0%
Error detection 2024
49.0% minimum GPR at MU + 4.5 % — MU error is the most detectable class

Gamma passing rate response to increasing MU error — VMAT

Udee et al., J Med Phys 49(1):56–63 (2024)

TG-218 action-limit application — Delta4 cohort scope
275
plans analysed
1 214
field deliveries
6 198
gamma analyses
Single largest published Delta4 cohort applying AAPM TG-218 statistical action limits to SRS and SBRT.
SRS / SBRT 2020
275 SRS / SBRT plans · 1 214 field deliveries · 6 198 gamma analyses on Delta4 and comparator devices

Application of TG-218 action limits to SRS and SBRT pre-treatment patient-specific QA

Journal of Radiosurgery and SBRT 7(2):135–147 — Xia, Adamson, Zlateva, Giles

Single-target VMAT SRS — GPR by tightening gamma criterion
γ 3 %/3 mm
98.81%
γ 3 %/2 mm
98.06%
γ 3 %/1 mm
93.64%
γ 2 %/1 mm
88.50%
SRS / SBRT 2020
98.81% mean gamma passing rate at 3 %/3 mm — held above 93 % even at the strict 3 %/1 mm criterion

Delta4 gamma passing rate by criterion — single-target intracranial SRS (n = 24)

Xia et al., J Radiosurg SBRT 7(2):135–147 (2020)

SBRT all-sites — Delta4 vs TG-218 action limit
4 %/1 mm
TG-218 action limit
90 % GPR required
vs
90.27%
Delta4 cohort result
0 % plans failed the threshold
SRS / SBRT 2020
0% failure rate at the TG-218 4 %/1 mm action limit across the SBRT cohort

Delta4 holds tolerance at 4 %/1 mm across all SBRT sites (n = 66)

Xia et al., J Radiosurg SBRT 7(2):135–147 (2020)

MR-linac Delta4 validation — clinical readiness
0.35 T
ViewRay MRIdian
1.5 T
Elekta Unity
Daily
adaptive RT cycle
Validated separately in 0.35 T (Cusumano 2020) and 1.5 T (Houweling 2017, PubMed 29176067). The MR-compatible Delta4+ is now the QA standard at UMC Utrecht, Heidelberg, Miami Cancer Institute and other adaptive-RT programmes.
MR-linac 2020
36 plans re-planned on MR-compatible Delta4 and delivered — characteristics comparable to the non-MR version

Clinical validation of the MR-compatible Delta4 QA system in a 0.35 T MR-linac

Physica Medica — Cusumano et al. (PMC8035559)

Pre-treatment IMRT QA — gamma passing-rate range
99.6%
Cohort minimum
lowest plan in the series
vs
100%
Cohort maximum
multiple plans matched the calculated dose
IMRT pre-treatment 2020
99.6% minimum gamma passing rate across the pre-treatment IMRT QA cohort with anatomy-based 3D DVH analysis

Evaluation of Delta4DVH Anatomy in 3D patient-specific IMRT quality assurance

Journal of Applied Clinical Medical Physics (PMC7388137)

Detector hardware (foundational characterisation)
1 069
p-type diodes
5 mm
inner resolution
2 ⊥
orthogonal panels
2.5 mm phantom-shift technique doubles the effective resolution for SRS work. Original Delta4 characterisation continues to underpin the Phantom+ device.
Foundational 2009
1 069 p-type diodes on two near-orthogonal panels · 5 mm spatial resolution in the inner area · the device characterised in the original 2009 validation paper

Evaluation of the Delta4 phantom for IMRT and VMAT verification

Medical Physics — Bedford et al. (PubMed 19384007)

Brochures & references

Manufacturer comparison material. Peer-reviewed citations are inline on the cards above.