Knowledge Hub · CRP™ Dispensing System
CRP isn\'t a shielded hot cell. It\'s the dispensing automation that drops into one — typically the FLEX in our setup. This page explains, in plain language, what CRP does (precise F-18 vial dispensing, hands-out-of-cell), what it leaves to the host cell (shielding, Grade A environment, AERB licensing), and why the SYNT → FLEX + CRP stack is the Saxsons-supplied package for a modern Indian cyclotron radiopharmacy.
Where CRP sits
Step 1
Cyclotron
Particle accelerator makes the F-18
Step 2
SYNT
Automated chemistry turns it into FDG (or another PET tracer)
Step 3
FLEX + CRP
FLEX is the Grade A cell; CRP is the automation inside it
Step 4
Patient
Syringe leaves the cell, scanned within hours
Why this matters
It's a module, not a hot cell
Most things called "dispensing systems" come with their own shielded box. CRP is the opposite — it's the dispensing automation engineered to drop into a shielded hot cell you already have (or are buying alongside, like the FLEX). The host cell provides the shielding and the GMP environment; CRP brings the precision and the hands-out-of-cell workflow.
Based on: CRP product page — "compact dimensions, can be installed in any type of shielded laminar flow cell"
Read source ↗Better than 1% precision
Patient dose accuracy starts with how precisely the volume is dispensed. (the manufacturer )guarantees CRP volume / weight deviation stays under 1% of target. That's the precision floor a modern radiopharmacy expects from an automated unit-dose bench.
Based on: CRP product page — "deviation from the target volume (weight) guaranteed to be less than 1%"
Read source ↗Open and closed vials
CRP Compact dispenses open vials (with rubber stopper + crimped aluminum-ring cap) and adds closed-vial via septum piercing as an option. CRP Compact plus does open-vial dispensing with either crimped or push-fit capping. The same module handles the F-18 unit-dose workflow shapes you'll meet day-to-day.
Based on: CRP product page — Compact and Compact plus variant descriptions
Read source ↗Annex 1 compliant
The European pharmaceutical rules require unit-dose dispensing of sterile injectables to happen under aseptic conditions. CRP is positioned by (the manufacturer )as compliant with EU GMP Annex 1, the sterile-medicines rulebook (revised 2022). The host cell provides the Grade A environment; CRP runs the dispensing process inside it.
Based on: CRP product page — "compliant with EU GMP Annex 1 regulations"
Read source ↗100 units worldwide
(the manufacturer )publishes a 100-units-installed install base for CRP. For an Indian cyclotron site evaluating dispensing automation, that's a meaningful reference base — the device exists, it ships, it works in clinical practice.
Based on: CRP product page — "100 CRP installed around the world"
Read source ↗Pairs with FLEX
SYNT is where the chemistry happens; FLEX is the Grade A shielded cell where unit doses are drawn; CRP is the automation inside FLEX that actually does the dispensing. Buying all three as a the manufacturer stack means one calibration chain, one teleassistance contract, and one consistent audit trail across the cyclotron radiopharmacy.
Based on: SYNT + FLEX + CRP product pages
Read source ↗CRP at a glance
< 1%
Volume deviation
(the manufacturer )guaranteed precision
100+
Units worldwide
manufacturer-published install base
Annex 1
EU GMP framework
Sterile-conditions compliant
F-18
India primary use
FDG unit-dose dispensing
Scope of this page
CRP is a dispensing module, not a hot cell. Lead shielding, Grade A environment and AERB licensing all sit with the host cell (typically the FLEX in a Saxsons-supplied Indian setup). The F-18 primary-use focus is Saxsons-supplied market reality — the CRP public page uses generic "radiopharmaceutical" language and does not name specific isotopes. The "compliant with EU GMP Annex 1" claim is Tema\'s marketing language; CRP is the automation that supports an Annex 1 workflow, but certification of the radiopharmacy programme is the operator\'s responsibility.
CRP product page, brochure PDF, and the FLEX hot cell CRP typically lives inside for an Indian cyclotron radiopharmacy.
Manufacturer page with the CRP Compact / Compact plus specification and Vimeo product demos.
CRP Compact / CRP Compact plus product brochure (2024 edition).
The Grade A shielded cell CRP typically lives inside for an Indian cyclotron radiopharmacy.
Where next
Product page →
CRP specs and demos
Compact vs Compact plus, vial-type matrix, brochure, two the manufacturer Vimeo product demos.
Host cell →
FLEX dispensing hot cell
The Grade A shielded hot cell CRP typically lives inside — 100 mm Pb India config.
For the radiopharmacist →
Automation scope
What CRP automates and what stays manual — for the QA / radiopharmacist team.