Saxsons Group

Radiopharmacist · Per-isotope carrier selection

Seven isotope groups — and the carrier each one calls for.

The carrier tier is set by the radiopharmaceutical class — gamma energy, per-dose activity, β contribution, per-shift cumulative. Here is the selection sheet across the SPECT, PET and theranostic workflow.

Tc-99m SPECT — MDP, MIBI, ECD, MAG3, DMSA

Recommended carrier · 3 mm Pb · SS 304 (RPSYC-1-08-3-C-S-0) or SS 202 (RPSYC-1-08-3-B-S-0)
Rule · Routine cardiac / oncology / renal SPECT — 25–40 unit doses per shift; 3 mm Pb is the workhorse transport tier.
Why · At 140 keV, 3 mm Pb gives ~ 11 HVL → > 99.95 % attenuation. The 6 mm tier is over-spec for routine SPECT activity.

I-131 thyroid therapy (low-activity ablation)

Recommended carrier · 6 mm Pb · SS 202 (RPSYC-1-09-6-B-S-0)
Rule · Diagnostic I-131 + post-thyroidectomy ablation prep at the lower activity range. 6 mm Pb all sides handles the 364 keV gamma.
Why · HVL at 364 keV ~ 3.0 mm; 6 mm wall = ~ 2 HVL. High-activity I-131 therapy capsules step up to the 12 mm tier.

FDG / Ga-68 / Cu-64 routine PET

Recommended carrier · 6 mm + 12 mm lateral (RPSYC-1-09-12-B-S-0) OR 6 mm all sides (RPSYC-4-17-6-B-S-0)
Rule · Per-dispense activity 350–550 MBq · per-shift cumulative 10–22 GBq. The 6+12 mm lateral tier targets the lateral wall closest to the operator hand during carry.
Why · At 511 keV, the 12 mm lateral wall delivers ~ 3 HVL (~ 88 %) — the engineering choice for the hand-side of the carry.

High-activity PET multi-dose source vial

Recommended carrier · 12 mm Pb all sides · 230×125×95 mm (RPSYC-1-07-12-B-S-0)
Rule · High-throughput PET dispensing 30+ unit doses per shift from a source vial. The premium 12 mm all-sides tier covers the cumulative dose budget.
Why · Multi-dose dispense workflow keeps the carrier in use across the full shift; the all-sides 12 mm tier removes the lateral / front / back gradient.

Lu-177 theranostic — PRRT / PSMA-617 / FAPI

Recommended carrier · Hybrid Pb + acrylic · 254×127×127 mm (RPSYC-7-17-3-B-A-0)
Rule · Per-patient 4–7.4 GBq Lu-177 dose · β + γ doublet at 113 / 208 keV. The dedicated Lu-177 hybrid carrier handles both modalities.
Why · Pb handles the γ; acrylic inner stops the β before bremsstrahlung develops against the lead inner. Lu-177 needs both layers because the activity is high and the emission is mixed.

Y-90 SIR-T microspheres / radiosynovectomy

Recommended carrier · β-γ hybrid · Pb + 6 mm Perspex (RPSYC1-276-81-65-9-9-B-D-08-0)
Rule · Per-dose 1.1–3.0 GBq Y-90 · pure-beta endpoint 2.28 MeV. Perspex inner is the radiation-safety construction.
Why · High-energy Y-90 beta generates substantial bremsstrahlung in lead. Without the Perspex inner the carrier becomes a bremsstrahlung source itself.

P-32 / Sr-89 — myeloproliferative / bone palliation

Recommended carrier · β-γ hybrid · 9″×9″ acrylic + Pb (RPSYC-201-86-76-9-9-B-08-0) or 6×20 (RPSYC-6-20-3-B-B-0)
Rule · Per-dose 18.5–185 MBq · pure-beta isotopes for myeloproliferative work and bone-pain palliation. Same Perspex / acrylic principle as Y-90.
Why · Same bremsstrahlung physics; lower activity per dose than Y-90 SIR-T but the hybrid construction is still the right answer.