Medical Physicist's Notes · QA Reference Sources
One reference set, three annualphysicist workflows.
The four-isotope NIST-traceable reference set powers three distinct annual physicist workflows — dose-calibrator accuracy, dose-calibrator linearity, and well-counter energy + efficiency calibration. This post walks each one in checklist form so the annual QA dossier is built directly off the worksheet.
Annual accuracy — dose calibrator
Six-step checklist · PASS Δ ± 10 %
- 1
Warm-up the dose calibrator and let the source set come to room temperature alongside it. Thermal drift is the #1 single-day variance noise.
- 2
Read background; subtract; verify the calibrator is on the correct isotope setting before each source.
- 3
Insert source in the standard orientation. Read three times, take the mean.
- 4
Decay-correct the certificate activity to the time of measurement. Δ = (A_measured − A_expected) / A_expected × 100 %.
- 5
PASS criterion: Δ within ± 10 % across all four isotopes (AERB / AAPM TG-181 annual accuracy threshold).
- 6
Document the result in the annual QA dossier alongside the constancy trend log from the past year.
Source: AAPM TG-181 PET / Nuclear Medicine QA; AERB Safety Code for Nuclear Medicine Facility.
Annual linearity — dose calibrator
Five-step checklist · PASS deviation ≤ 5 %
- 1
Use the long-lived Cs-137 reference (T½ 30.1 y) as the activity-decade-spanning probe. Decay won't close the working range during the test.
- 2
Read the source through shielded attenuators producing known transmission factors (typically 5 attenuator pots producing 1× / 0.5× / 0.2× / 0.1× / 0.05× geometry).
- 3
Plot measured activity vs expected activity on a log-log axis. Fit line; expected slope = 1.0, intercept = 0.
- 4
PASS criterion: deviation from linearity ≤ 5 % across the clinical activity range (typically 37 MBq to 37 GBq).
- 5
Document the linearity plot in the annual dossier. Re-run after dose-calibrator service or chamber replacement.
Source: AAPM TG-181; AERB Safety Code for Nuclear Medicine Facility (Section on dose-calibrator QA).
Annual well counter — energy + efficiency calibration
Five-step checklist · cross-checks against dose-calibrator linearity
- 1
Energy calibration: use Ba-133 / Co-57 / Cs-137 / Co-60 sequentially to map the energy-channel response of the well counter's NaI(Tl) crystal.
- 2
Plot channel number vs photon energy; expected linear fit. Slope and intercept feed the spectrum-analysis software.
- 3
Counting efficiency: at each isotope, measure CPM at known activity; efficiency = CPM / (Bq × 60). Plot efficiency vs energy.
- 4
Re-run after PMT replacement, photomultiplier high-voltage adjustment, or annual scheduled QA.
- 5
Cross-check against the dose calibrator linearity result — well counter and dose calibrator should agree on the same Cs-137 activity to within their combined uncertainties (typically ± 10 %).
Source: AAPM TG-181; IAEA Quality Control of Nuclear Medicine Instruments (IAEA-TECDOC-602).